Your one stop Vaccination Clinic

Japanese Encephalitis Vaccine

Japanese Encephalitis Vaccine

We provide a full range of travel vaccinations and medication

Japanese Encephalitis

Japanese encephalitis (JE) is a flavirus mosquito-borne virus which affects the brain. Approximately 70,000 clinical cases occur in 24 countries (WHO, 2015). They are prevalent around rural farming areas in Asia.

Vaccination Pricing

£110 Per dose
£220 Per Course

Signs & Symptoms

Most human infections with JE virus do not result in symptoms.

When symptoms do occur they include:

  • Mostly asymptomatic

  • Fever

  • Headache

  • Confusion

  • Death rate is high in symptomatic cases admitted to hospital

James Pharmacy & Travel Clinic

General Contact & Travel Vaccination

Tel: 01242 522 880

Email: cheltenhamtravelclinic@raylane.co.uk

19 St Georges Road, Cheltenham GL50 3DT

Wymans Brook Pharmacy & Travel Clinic

General Contact & Travel Vaccination

Tel: 01242 221 988

Email: cheltenhamtravelclinic@raylane.co.uk

Unit 1, Windyridge Rd, Cheltenham GL50 4RA

The Vaccination

Ages (Years) Doses Required Schedule Time before travel Boost required at
3 – 85 2 0, 28 days Last dose up to day before* 1-2 years
18 – 65 2 0, 7 days** Last dose up to day before* 1-2 years

*This vaccination is at its most effective when given time to develop adequate immunity. Some immunity will be present if you get the vaccine up to the day before your trip.
** accelerated schedule

Japanese Encephalitis (JE) is a viral brain infection transmitted by mosquitoes, primarily found in rural and agricultural parts of Asia and the western Pacific. It is caused by the Japanese encephalitis virus, a flavivirus related to dengue and West Nile virus. While most infections are asymptomatic, a small proportion can lead to severe neurological illness with high fatality rates and long-term disability.


JE is spread through the bite of infected Culex mosquitoes, which breed in rice paddies and stagnant water. The virus circulates between mosquitoes, pigs, and wading birds. It does not spread from person to person. Prevention includes mosquito bite avoidance—using insect repellent, nets, and protective clothing—and vaccination. The JE vaccine (Ixiaro) is recommended for those spending extended periods in rural parts of endemic countries or during peak transmission seasons.

Mild symptoms, if present, may include fever and headache. Severe disease can lead to inflammation of the brain (encephalitis), resulting in high fever, neck stiffness, seizures, coma, and permanent neurological damage. The case fatality rate in severe cases can be as high as 30%, with many survivors experiencing long-term complications.


A two-dose course of Ixiaro, given 28 days apart, offers protection for at least 1–2 years. A booster dose after 1 year extends immunity further. In some cases, accelerated schedules are available for last-minute travellers.


JE vaccination is recommended for travel to rural areas of countries such as India, Nepal, Cambodia, Thailand, Vietnam, Indonesia, China, and Japan, particularly if travelling during the rainy season or for extended stays.



Side effects are generally mild, such as soreness at the injection site, mild headache, or fatigue. Serious reactions are extremely rare. The vaccine provides strong protection and peace of mind when visiting high-risk areas.

Book your Japanese encephalitis vaccine with us and travel confidently with the right protection in place.




Use the map below to identify areas of risk for travel.

Simply call the clinic of your choice or send us an email enquiry, and our travel specialists will get back to you as soon as possible.

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The Cheltenham Travel Clinic offers a wide range of vaccines and travel vaccinations.

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Competitive Pricing

We offer competitive pricing on our vaccinations to ensure that essential healthcare is both affordable and accessible to everyone.

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